反应详情

To a solution of 3.13 g (10 mmoles) of 2-[3-chloro-4-(4-chloropyrazol-1-yl)phenyl]propionic acid ethyl ester in 20 ml of dimethyl formamide there are added dropwise, at room temperature, 15 ml of hydrazine hydrate. Stirring is continued for a further 2 hours at room temperature, followed by pouring on to ice, extraction with methylene chloride, drying of the organic phase and concentration. 2-[3-chloro-4-(4-chloropyrazol-1-yl)phenyl]propionic hydrazide is obtained.

1. customdrying of the organic phase and concentration