反应详情

温度

100 °C

17.0 g. (0.15 mol) of cysteaminium chloride and 19.8 g. (0.3 mol) of potassium hydroxide are boiled for 3 hours on a water separator in 180 ml. of toluene. 24.6 g. (0.1 mol) of 2-chlorothioxanthone and 180 mol of dimethylpropyleneurea are added to the evaporated residue, and the mixture is stirred for 20 hours at 100° C. The reaction mixture is poured into 1 l of 2N hydrochloric acid and the aqueous phase is extracted with ethyl acetate. The aqueous phase then adjusted to pH 10 and extracted with ethyl acetate. Work-up of the organic phase gives 24.0 g. of the analytically pure compound IIIb.

1. extractionthe aqueous phase is extracted with ethyl acetate
2. extractionextracted with ethyl acetate
3. customgives 24.0 g