p-Methoxybenzophenonoxime → 1-(4-Methoxyphenyl)-1-phenylmethanamine

HRID 1735563Notes

Reaction equation

HRID 1735563 reaction equation
[CH3:1][O:2][C:3]1[CH:17]=[CH:16][C:6]([C:7](=[N:14]O)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:5][CH:4]=1.C([O-])(=O)C.[NH4+].C([BH3-])#N.[Na+]>[Cl-].[Cl-].[Cl-].[Ti+3]>[CH3:1][O:2][C:3]1[CH:17]=[CH:16][C:6]([CH:7]([NH2:14])[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 185567p-MethoxybenzophenonoximeHCID 517165Ammonium AcetateHCID 5003444Sodium cyanoborohydride

Product 1

HCID 3500411-(4-Methoxyphenyl)-1-phenylmethanamineYield 76.9%

Reagents, catalysts & solvents 1

HCID 10313229titanium(III) trichlorideCatalyst

Procedure

Following a procedure similar to that described in Preparation 12, but using 9.4 g of 4-methoxybenzophenone oxime, 33.9 g of ammonium acetate, 7.46 g of sodium cyanoborohydride, and 79 ml of a 17-19% by volume aqueous solution of titanium trichloride, 6.78 g of the title compound were obtained as an oily substance.

Workup

  1. customthat described in Preparation 12

Sources & evidence

ORD record
ord-8590e83fe4994ba288f6cd8734966070
Source dataset
uspto-grants-1996_07
Patent number
US05536714

Reaction notes

Loading…