Dimethylformamide → Ethyl 3-methoxy-4-[[1-[2-[3-methoxy-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]pyrrolidin-2-yl]methoxy]benzoate

HRID 173624Notes

Reaction equation

HRID 173624 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12][c:13]1[O:14][CH2:15][CH:16]1[NH:17][CH2:18][CH2:19][CH2:20]1.[CH3:21][O:22][c:23]1[cH:24][c:25]([CH2:40][C:41](=[O:42])[OH:43])[cH:26][cH:27][c:28]1[NH:29][C:30](=[O:31])[NH:32][c:33]1[c:34]([CH3:39])[cH:35][cH:36][cH:37][cH:38]1.[CH3:44][CH2:45][N:46]([CH2:47][CH3:48])[CH2:49][CH3:50].[CH3:56][CH2:57][O:58][C:59]([CH3:60])=[O:61].[O:51]=[CH:52][N:53]([CH3:54])[CH3:55]>>[CH3:1][O:2][c:3]1[cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12][c:13]1[O:14][CH2:15][CH:16]1[N:17]([C:41]([CH2:40][c:25]2[cH:24][c:23]([O:22][CH3:21])[c:28]([NH:29][C:30](=[O:31])[NH:32][c:33]3[c:34]([CH3:39])[cH:35][cH:36][cH:37][cH:38]3)[cH:27][cH:26]2)=[O:42])[CH2:18][CH2:19][CH2:20]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 114498403-Methoxy-4-o-tolylureidophenylacetic acidHCID 73241633Ethyl 3-methoxy-4-(pyrrolidin-2-ylmethoxy)benzoate

Product 1

HCID 91051404Ethyl 3-methoxy-4-[[1-[2-[3-methoxy-4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]pyrrolidin-2-yl]methoxy]benzoate

Sources & evidence

ORD record
ord-e0beb0063d4d40cf99a804f578dff2b1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…