Chloride → 1-(1-Phenylethyl)-4-(4-phenylmethoxyphenyl)piperidin-3-ol

HRID 173663Notes

Reaction equation

HRID 173663 reaction equation
[BH4-:29].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([C:15]2=[CH:20][CH2:19][N:18]([CH:21]([CH3:22])[c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[CH2:17][CH2:16]2)[cH:13][cH:14]1.[CH2:43]([CH2:44][O:45][CH3:46])[O:47][CH3:48].[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[Cl-:35].[Na+:30].[Na+:32].[Na+:36].[OH-:31].[OH:33][OH:34]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([CH:15]2[CH2:16][CH2:17][N:18]([CH:21]([CH3:22])[c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[CH2:19][CH:20]2[OH:31])[cH:13][cH:14]1

Participants

9

Reactant 8

HCID 312ChlorideHCID 784Hydrogen PeroxideHCID 923Sodium ion3×HCID 961HydroxideHCID 80711,2-DimethoxyethaneHCID 8857Ethyl AcetateHCID 28123BorohydrideHCID 217130754-(4-Benzyloxy-phenyl)-1-(1-phenyl-ethyl)-1,2,3,6-tetrahydro-pyridine

Product 1

HCID 217130731-(1-Phenylethyl)-4-(4-phenylmethoxyphenyl)piperidin-3-ol

Sources & evidence

ORD record
ord-5197cacee10f4e11b8fd9b980cf7e949
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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