Hydrochloric Acid → HCID 19007852, compound

HRID 1741636Notes

Reaction equation

HRID 1741636 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]([CH:10]1[CH2:16][CH:15]2[N:17]([CH3:18])[CH:12]([CH2:13][CH2:14]2)[CH2:11]1)=O.[ClH:19].C([O-])(=[O:22])C.[NH4+:24]>C(O)C.O>[ClH:19].[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1/[C:8](/[CH:10]1[CH2:11][CH:12]2[N:17]([CH3:18])[CH:15]([CH2:14][CH2:13]2)[CH2:16]1)=[N:24]\[OH:22]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 517165Ammonium AcetateHCID 9837778HCID 9837778, compound

Product 1

HCID 19007852HCID 19007852, compound

Reagents, catalysts & solvents 1

HCID 19096565Water ethanolSolvent

Procedure

A mixture of (2-fluorophenyl)(8-methyl-8-azabicyclo[3.2.1 ]octan-3-yl)methanone (29.5 g), hydroxylmine hydrochloride (16.5 g) and ammonium acetate (27.5 g) were heated in 80 ml of refluxing ethanol-water (3:1 mixture) for 19 hours. The mixture was and the precipitated product was collected (25.2g).

Workup

  1. customthe precipitated product was collected (25.2g)

Sources & evidence

ORD record
ord-7b2a7a50933c434d80cd14a15b94bcce
Source dataset
uspto-grants-1994_08
Patent number
US05334599

Reaction notes

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