Methylamine → HCID 15227517, compound

HRID 1742209Notes

Reaction equation

[N:1]1[CH:6]=[CH:5][C:4]([CH:7]=O)=[CH:3][CH:2]=1.[CH3:9][NH2:10].[C:11]([O:15]C(=O)CC)(=O)[CH2:12][CH3:13]>>[CH3:9][N:10]([CH2:7][C:4]1[CH:3]=[CH:2][N:1]=[CH:6][CH:5]=1)[C:11](=[O:15])[CH2:12][CH3:13]

Participants

Reactant 3

HCID 6329Methylamine

HCID 133894-Pyridinecarboxaldehyde

HCID 31263Propionic anhydride

Product 1

HCID 15227517HCID 15227517, compoundYield 72%

Procedure

Pyridine-4-carboxaldehyde, methyl amine, and propionic anhydride were reacted on a 0.1 mole scale in a manner similar to that given for Example 1 to give the desired amide (12.72 g, 72%).

Sources & evidence

ORD record: ord-12e2a81052a64bb7bbd6cd036ae9ff0a
Source dataset: uspto-grants-1994_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05338738

Reaction notes

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