Butyl iodide → HCID 19005898, compound

HRID 1742822Notes

Reaction equation

[NH2:1][C:2]1[S:3][CH:4]=[CH:5][C:6]=1[C:7]([O:9][CH3:10])=[O:8].[CH2:11](I)[CH2:12][CH3:13].NC1C=CSC=1C(OC)=O.C(I)CCC>>[CH2:11]([NH:1][C:2]1[S:3][CH:4]=[CH:5][C:6]=1[C:7]([O:9][CH3:10])=[O:8])[CH2:12][CH3:13]

Participants

Reactant 4

HCID 10962Butyl iodide

HCID 336431-Iodopropane

HCID 78381Methyl 2-amino-3-thenoate

HCID 89652Methyl 3-amino-2-thiophenecarboxylate

Product 1

HCID 19005898HCID 19005898, compoundYield 54%

Procedure

In the same manner as in Reference Example 1-1), methyl 2-aminothiophene-3-carboxylate [Chem. Bet. 98, 3571 (1965)]and n-propyl iodide were used in place of methyl 3-aminothiophene-2-carboxylate and n-butyl iodide to obtain 10.76 g (54.0%) of Compound (h-1).

Sources & evidence

ORD record: ord-972eea0c5a2c4c4fbe97c03ae8f3a609
Source dataset: uspto-grants-1994_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05342843

Reaction notes

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