Benzaldehyde → HCID 11075340, compound

HRID 1755829Notes

Reaction equation

HRID 1755829 reaction equation
[CH3:1][C:2]1([CH3:10])[O:9][C:7](=[O:8])[CH2:6][C:4](=[O:5])[O:3]1.[CH:11](=O)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>C1(C)C=CC=CC=1>[CH3:1][C:2]1([CH3:10])[O:9][C:7](=[O:8])[CH:6]([CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:4](=[O:5])[O:3]1

Participants

4

Reactant 2

HCID 240BenzaldehydeHCID 162492,2-Dimethyl-1,3-dioxane-4,6-dione

Product 1

HCID 11075340HCID 11075340, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Meldrum's acid (73) is treated with benzaldehyde in the presence of borane-triethylamine complex in toluene. The product is isolated by flash chromatography over silica gel to give (74).

Workup

  1. customThe product is isolated by flash chromatography over silica gel

Sources & evidence

ORD record
ord-86569f27a1064d99964ab736ddfa01c7
Source dataset
uspto-grants-1995_08
Patent number
US05438118

Reaction notes

Loading…