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HRID1756565

反应详情

EQUATION

反应方程式

HRID 1756565 的结构方程式

REACTANTS

反应物

4
反应SMILES：O=C1Nc2ccccc2C1=O
HCID7054

Isatin

C8H5NO2

反应SMILES：O=c1[nH]c2ccc([N+](=O)[O-])cc2c(=O)o1
HCID20821

2H-3,1-Benzoxazine-2,4(1H)-dione, 6-nitro-

C8H4N2O5

反应SMILES：O=c1[nH]c2ccc(Cl)cc2c(=O)o1
HCID78480

2H-3,1-Benzoxazine-2,4(1H)-dione, 6-chloro-

C8H4ClNO3

反应SMILES：O=C1Nc2ccc(F)cc2C1=O
HCID236566

5-Fluoroisatin

C8H4FNO2

PRODUCTS

产物

1
反应SMILES：O=C1c2ccccc2-n2c1nc1ccc([N+](=O)[O-])cc1c2=O
HCID336271

未命名化合物

收率 24%

AUXILIARIES

试剂、催化剂与溶剂

1
反应SMILES：CN(C)C=O
溶剂HCID6228

Dimethylformamide

C3H7NO

PROCEDURE

实验过程

Using the procedure in Example 12, and substituting NMP for DMF, 5-nitroisatoic anhydride for 5-chloroisatoic anhydride and isatin for 5-fluoroisatin gave 495 mg (24%) of the title compound: mp 349° C. (dec); 1H NMR(CDCl3)δ 7.46-7.54 (m, 1H), 7.84-8.00 (m, 3H), 8.18-8.22 (m, 1H), 8.62-8.68 (m, 2H).