Carbon Tetrachloride → HCID 15290414, compound

HRID 1757151Notes

Reaction equation

HRID 1757151 reaction equation
[F:1][C:2]1[CH:24]=[CH:23][CH:22]=[C:21]([F:25])[C:3]=1[C:4]([NH:6][C:7]1([CH2:19][OH:20])[C:16]2[C:11](=[CH:12][C:13]([O:17][CH3:18])=[CH:14][CH:15]=2)[CH2:10][CH2:9][CH2:8]1)=O.C(Cl)(Cl)(Cl)Cl.CN.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>C(#N)C>[F:25][C:21]1[CH:22]=[CH:23][CH:24]=[C:2]([F:1])[C:3]=1[C:4]1[O:20][CH2:19][C:7]2([C:16]3[C:11](=[CH:12][C:13]([O:17][CH3:18])=[CH:14][CH:15]=3)[CH2:10][CH2:9][CH2:8]2)[N:6]=1

Participants

6

Reactant 4

HCID 5943Carbon TetrachlorideHCID 6329MethylamineHCID 11776TriphenylphosphineHCID 19389969HCID 19389969, compound

Product 1

HCID 15290414HCID 15290414, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

To a suspension of 600 mg (0.0017 mol) of the product of Step D in 9 mL of acetonitrile was added 1.8 mL CCl4 and 264 mg (0.0026 mol) of methylamine. Then, 678 mg (0.0026 mol) of triphenylphosphine was added. The mixture was stirred at ambient temperature for 15 minutes.

Sources & evidence

ORD record
ord-f2fe3ff327514e048a30f6c717d25778
Source dataset
uspto-grants-1995_08
Patent number
US05444079

Reaction notes

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