Triethylamine → HCID 19387524, compound

HRID 1757315Notes

Reaction equation

HRID 1757315 reaction equation
[NH:1]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8][O:7][CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.C(N(CC)CC)C.[C:20](Cl)(=[O:25])[C:21]([CH3:24])([CH3:23])[CH3:22]>C(Cl)Cl.CN(C1C=CN=CC=1)C>[C:21]([C:20]([N:1]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8][O:7][CH2:6][CH2:5][O:4][CH2:3][CH2:2]1)=[O:25])([CH3:24])([CH3:23])[CH3:22]

Participants

6

Reactant 3

HCID 8471TriethylamineHCID 62493Pivaloyl chlorideHCID 5458171,4,7-Trioxa-10-azacyclododecane

Product 1

HCID 19387524HCID 19387524, compound

Reagents, catalysts & solvents 2

HCID 142844-(Dimethylamino)pyridineCatalystHCID 6344DichloromethaneSolvent

Procedure

3.81 mmol of 1-aza-4,7,10-trioxacyclododecane are dissolved in 50 ml of CH2Cl2. 0.6 ml of triethylamine are added and 0.1 g of DMAP (=4-dimethylaminopyridine) is added as catalyst 3.82 mmol of pivalyl chloride are subsequently added, and the mixture is stirred at room temperature for 18 hours.

Workup

  1. additionare subsequently added

Sources & evidence

ORD record
ord-c5136ffb43104d5ca68aaea6563c9d20
Source dataset
uspto-grants-1995_08
Patent number
US05445762

Reaction notes

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