Methane → HCID 178419983, compound

HRID 1762113Notes

Reaction equation

HRID 1762113 reaction equation
[NH2:1][C:2]1[C:10]([NH2:11])=[CH:9][C:5]2[N:6]=[CH:7][NH:8][C:4]=2[CH:3]=1.[N:12]1[CH:17]=[CH:16][C:15]([CH:18]=O)=[CH:14][CH:13]=1.Cl.C>>[N:12]1[CH:17]=[CH:16][C:15]([C:18]2[NH:1][C:2]3[CH:3]=[C:4]4[N:8]=[CH:7][NH:6][C:5]4=[CH:9][C:10]=3[N:11]=2)=[CH:14][CH:13]=1

Participants

5

Reactant 4

HCID 297MethaneHCID 313Hydrochloric AcidHCID 133894-PyridinecarboxaldehydeHCID 27731931H-benzimidazole-5,6-diamine

Product 1

HCID 178419983HCID 178419983, compound

Procedure

14.8 g. (100 mMole) 5,6-diaminobenzimidazole, 10.7 g. (100 mMole) pyridine-4-aldehyde and 5 ml. concentrated hydrochloric acid are heated to the boil under reflux. After the solution has been clarified with active charcoal, it is evaporated and the residue is digested with a little water. After suction filtration and drying, there are obtained 6.98 g. (29% of theory) of the desired product in the form of colourless crystals of the hydrochloride; m.p.>280° C.

Workup

  1. temperatureunder reflux
  2. customis evaporated
  3. filtrationAfter suction filtration
  4. customdrying
  5. customthere are obtained 6.98 g

Sources & evidence

ORD record
ord-3e29ccdee1de4bbe881e8b851c31b8ca
Source dataset
uspto-grants-1989_05
Patent number
US04831032

Reaction notes

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