反应详情

A solution of 121 g of 2-(3-benzo[b]furanyl)-ethylamine and 300 mL of ethyl formate was heated at 60° C. for 3 hours, poured into 2N HCl and washed with methylene chloride which in turn was washed with 5% sodium hydroxide (w/v), dried (Na2SO4), charcoaled and concentrated to give 118 g of product.

1. washwashed with methylene chloride which in turn
2. washwas washed with 5% sodium hydroxide (w/v)
3. dry with materialdried (Na2SO4)
4. concentrationconcentrated