Hydrochloric Acid → Hydrochloric Acid

HRID 176358Notes

Reaction equation

HRID 176358 reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][O:41][CH2:42]1.[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6](-[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:7]2[n:8][c:9]([C:20]([F:21])([F:22])[F:23])[cH:10][cH:11][c:12]2[c:13](=[O:19])[c:14]1[CH2:15][N:16]=[N+:17]=[N-:18].[CH3:31][CH2:32][O:33][C:34](=[O:35])[CH3:36].[CH3:43][OH:44].[ClH:30].[Pt:45](=[O:46])=[O:47]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6](-[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:7]2[n:8][c:9]([C:20]([F:21])([F:22])[F:23])[cH:10][cH:11][c:12]2[c:13](=[O:19])[c:14]1[CH2:15][NH2:16].[ClH:30]

Participants

8

Reactant 6

HCID 313Hydrochloric AcidHCID 887MethanolHCID 8857Ethyl AcetateHCID 312751,4-DioxaneHCID 345198Adams' catalystHCID 712083753-Azidomethyl-4-oxo-1-phenyl-7-trifluoromethyl-1,4-dihydro-[1,8]naphthyridine-2-carboxylic acid methyl ester

Product 2

HCID 313Hydrochloric AcidHCID 71208428Methyl 3-(aminomethyl)-4-oxo-1-phenyl-7-(trifluoromethyl)-1,8-naphthyridine-2-carboxylate

Sources & evidence

ORD record
ord-d88428b3f590403ca7d8c762924a51da
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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