Chloroform → 4-Piperidinecarboxylic acid

HRID 176634Notes

Reaction equation

HRID 176634 reaction equation
[CH3:12][CH2:13][N:14]([CH2:15][CH3:16])[CH2:17][CH3:18].[Cl:39][CH:40]([Cl:41])[Cl:42].[NH:1]1[CH2:2][CH2:3][CH:4]([C:5](=[O:6])[O:7][CH2:8][CH3:9])[CH2:10][CH2:11]1.[c:19]1([C:20]([Cl:21])([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[cH:34][cH:35][cH:36][cH:37][cH:38]1>>[NH:1]1[CH2:2][CH2:3][CH:4]([C:5](=[O:6])[OH:7])[CH2:10][CH2:11]1

Participants

5

Reactant 4

HCID 6212ChloroformHCID 6456Trityl chlorideHCID 8471TriethylamineHCID 70770Ethyl 4-piperidinecarboxylate

Product 1

HCID 37734-Piperidinecarboxylic acid

Sources & evidence

ORD record
ord-4e268c97d1e64818bed653d57f0905b8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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