Trifluoroacetic acid → HCID 17862517, compound

HRID 1766863Notes

Reaction equation

HRID 1766863 reaction equation
[C:1]([O:4][CH:5]([CH2:12][CH2:13][C:14]([O:16]CC1C=CC(OC)=CC=1)=[O:15])[C:6]([O:8][CH2:9][CH:10]=[CH2:11])=[O:7])(=[O:3])[CH3:2].C1(OC)C=CC=CC=1.FC(F)(F)C(O)=O>>[C:1]([O:4][CH:5]([C:6]([O:8][CH2:9][CH:10]=[CH2:11])=[O:7])[CH2:12][CH2:13][C:14]([OH:16])=[O:15])(=[O:3])[CH3:2]

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 7519AnisoleHCID 69143608HCID 69143608, compound

Product 1

HCID 17862517HCID 17862517, compoundYield 116.4%

Procedure

According to a similar procedure to that described in Example 1-(11), allyl 2-acetoxy-5-[(4-methoxybenzyl)oxy]-5-oxopentanoate (1.36 g, 3.88 mmol) obtained from Example 2-(3), anisole (1.50 g, 13.87 mmol), and trifluoroacetic acid (3 ml) were reacted, and the reaction mixture was worked up to afford the title compound (1.04 g, quantitative yield).

Sources & evidence

ORD record
ord-5e1daac0463447f782984959a434d10a
Source dataset
uspto-grants-2007_06
Patent number
US07230023B2

Reaction notes

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