p-Toluenesulfonic acid → HCID 22324104, compound

HRID 1767642Notes

Reaction equation

HRID 1767642 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([NH2:11])(=[O:10])=[O:9].[NH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1.CC1OC(C)O[CH:21]([CH3:26])O1.CC1C=CC([S:34](O)(=[O:36])=[O:35])=CC=1>>[CH3:21][CH:26]1[NH:1][C:2]2[CH:7]=[CH:6][C:5]([S:34]([N:12]3[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]3)(=[O:36])=[O:35])=[CH:4][C:3]=2[S:8](=[O:9])(=[O:10])[NH:11]1

Participants

5

Reactant 4

HCID 6101p-Toluenesulfonic acidHCID 8082PiperidineHCID 31264ParaldehydeHCID 728942-Aminobenzenesulfonamide

Product 1

HCID 22324104HCID 22324104, compound

Procedure

2-Aminobenzenesulfonamide was used as starting material for the following transformation sequence: Method C, Method A (using piperidine as amine), Method D, Method G [using paraldehyde and a cat. amount of TsOH]. M.p. 255–256° C.

Sources & evidence

ORD record
ord-fce01ea422384d4e8f83800ca58dadd6
Source dataset
uspto-grants-2007_06
Patent number
US07235548B2

Reaction notes

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