Dimethylformamide → 6-[2-[4-methoxy-7-(3-methyl-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-2-oxo-acetyl]-2-oxo-1-phenyl-7,8-dihydro-5H-1,6-naphthyridine-3-carbonitrile

HRID 177617Notes

Reaction equation

HRID 177617 reaction equation
[B-:42]([F:43])([F:44])([F:45])[F:46].[CH3:1][O:2][c:3]1[c:4]2[c:5]([c:6](-[n:9]3[n:10][c:11]([CH3:14])[n:12][cH:13]3)[n:7][cH:8]1)[nH:15][cH:16][c:17]2[C:18]([C:19](=[O:20])[OH:21])=[O:22].[CH3:78][CH2:79][O:80][C:81]([CH3:82])=[O:83].[CH:64]([N:65]([CH2:66][CH3:67])[CH:68]([CH3:69])[CH3:70])([CH3:71])[CH3:72].[O:23]=[c:24]1[n:25](-[c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[c:26]2[c:31]([cH:32][c:33]1[C:34]#[N:35])[CH2:30][NH:29][CH2:28][CH2:27]2.[O:73]=[CH:74][N:75]([CH3:76])[CH3:77].[n:47]1([O:48][C:49]([N:50]([CH3:51])[CH3:52])=[N+:53]([CH3:54])[CH3:55])[c:56]2[cH:57][cH:58][cH:59][cH:60][c:61]2[n:62][n:63]1>>[CH3:1][O:2][c:3]1[c:4]2[c:5]([c:6](-[n:9]3[n:10][c:11]([CH3:14])[n:12][cH:13]3)[n:7][cH:8]1)[nH:15][cH:16][c:17]2[C:18]([C:19](=[O:21])[N:29]1[CH2:28][CH2:27][c:26]2[n:25](-[c:36]3[cH:37][cH:38][cH:39][cH:40][cH:41]3)[c:24](=[O:23])[c:33]([C:34]#[N:35])[cH:32][c:31]2[CH2:30]1)=[O:22]

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 26255TetrafluoroborateHCID 81531DiisopropylethylamineHCID 130500O-benzotriazol-1-yl-tetramethyluroniumHCID 580260402-Oxo-1-phenyl-1,2,5,6,7,8-hexahydro-1,6-naphthyridine-3-carbonitrileHCID 596815922-(4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetic acid

Product 1

HCID 445556026-[2-[4-methoxy-7-(3-methyl-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-2-oxo-acetyl]-2-oxo-1-phenyl-7,8-dihydro-5H-1,6-naphthyridine-3-carbonitrile

Sources & evidence

ORD record
ord-cc6e7776e669453e81cffa8d5f944ce8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…