Water → N'-acetyl-2-[5-(4-fluorobenzyl)-3-pyridin-4-yl-1H-pyrazol-1-yl]acetohydrazide

HRID 177807Notes

Reaction equation

HRID 177807 reaction equation
[C:24]([n:25]1[cH:26][cH:27][n:28][cH:29]1)([n:30]1[cH:31][cH:32][n:33][cH:34]1)=[O:35].[C:36]([CH3:37])(=[O:38])[NH:39][NH2:40].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][c:7]2[cH:8][c:9](-[c:16]3[cH:17][cH:18][n:19][cH:20][cH:21]3)[n:10][n:11]2[CH2:12][C:13](=[O:14])[OH:15])[cH:22][cH:23]1.[O:46]=[CH:47][N:48]([CH3:49])[CH3:50].[OH2:51]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][c:7]2[cH:8][c:9](-[c:16]3[cH:17][cH:18][n:19][cH:20][cH:21]3)[n:10][n:11]2[CH2:12][C:13](=[O:14])[NH:40][NH:39][C:36]([CH3:37])=[O:38])[cH:22][cH:23]1

Participants

7

Reactant 6

HCID 962WaterHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 14039AcetohydrazideHCID 682631,1'-CarbonyldiimidazoleHCID 670925255-[(4-fluorophenyl)methyl]-3-(4-pyridinyl)-1H-Pyrazole-1-acetic acid

Product 1

HCID 67092526N'-acetyl-2-[5-(4-fluorobenzyl)-3-pyridin-4-yl-1H-pyrazol-1-yl]acetohydrazide

Sources & evidence

ORD record
ord-2f278042b69041d8ae1d5016ef6be01b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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