Allyl bromide → HCID 9910029, compound

HRID 1780015Notes

Reaction equation

HRID 1780015 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:10]2[O:20][C:19]3[CH:18]=[C:17]([OH:21])[CH:16]=[C:15]([OH:22])[C:14]=3[C:12](=[O:13])[CH:11]=2)=[CH:7][C:8]=1[OH:9].[H-].[Na+].[CH2:25](Br)[CH:26]=[CH2:27]>CN(C)C=O>[CH2:25]([O:22][C:15]1[C:14]2[C:12](=[O:13])[CH:11]=[C:10]([C:6]3[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[C:8]([O:9][CH2:4][CH:3]=[CH2:8])[CH:7]=3)[O:20][C:19]=2[CH:18]=[C:17]([O:21][CH2:7][CH:6]=[CH2:5])[CH:16]=1)[CH:26]=[CH2:27]

Participants

5

Reactant 3

HCID 7841Allyl bromideHCID 24758Sodium hydrideHCID 5281612Diosmetin

Product 1

HCID 9910029HCID 9910029, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent2×

Conditions

Temperature
40 °C

Procedure

30 g of diosmetin in 300 ml of dimethylformamide are added to a suspension of 11.7 g of sodium hydride in 150 ml of dimethylformamide. The mixture is maintained at 40° C. with stirring until the evolution of gas has ceased. 48 g of allyl bromide are then added and stirring at 40° C. is continued for 22 hours.

Workup

  1. stirringstirring at 40° C.

Sources & evidence

ORD record
ord-4bd97bc95075499cb08dfba5100645c4
Source dataset
uspto-grants-1997_05
Patent number
US05629339

Reaction notes

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