Hydrochloric Acid → tert-butyl N-[3-propan-2-yl-3-[3-(trifluoromethyl)-7,8-dihydro-5H-1,6-naphthyridine-6-carbonyl]cyclopentyl]carbamate
Reaction equation
[C:17]([CH3:18])([CH3:19])([CH3:20])[O:21][C:22](=[O:23])[NH:24][CH:25]1[CH2:26][C:27]([C:30](=[O:31])[OH:32])([CH:33]([CH3:34])[CH3:35])[CH2:28][CH2:29]1.[CH3:48][N:49]([CH3:50])[c:51]1[cH:52][cH:53][n:54][cH:55][cH:56]1.[CH:36]([N:37]([CH:38]([CH3:39])[CH3:40])[CH2:41][CH3:42])([CH3:43])[CH3:44].[Cl:45][CH2:46][Cl:47].[ClH:1].[ClH:2].[F:3][C:4]([c:5]1[cH:6][n:7][c:8]2[c:13]([cH:14]1)[CH2:12][NH:11][CH2:10][CH2:9]2)([F:15])[F:16]>>[F:3][C:4]([c:5]1[cH:6][n:7][c:8]2[c:13]([cH:14]1)[CH2:12][N:11]([C:30]([C:27]1([CH:33]([CH3:34])[CH3:35])[CH2:26][CH:25]([NH:24][C:22]([O:21][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:23])[CH2:29][CH2:28]1)=[O:31])[CH2:10][CH2:9]2)([F:15])[F:16]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-872da7d5e17f41fe9d040e8f25ad93f8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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