Benzenesulfonyl chloride → Benzenesulfonyl hydrazide

HRID 1795127Notes

Reaction equation

HRID 1795127 reaction equation
[C:1]1([S:7](Cl)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.O.[NH2:12][NH2:13]>>[C:1]1([S:7]([NH:12][NH2:13])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 7369Benzenesulfonyl chlorideHCID 24654Hydrazine hydrate (1:1)

Product 1

HCID 65723Benzenesulfonyl hydrazide

Procedure

Benzenesulfonohydrazide is prepared from benzenesulfonyl chloride (500 mg, 2.83 mmol) and hydrazine monohydrate (0.42 mL, 8.49 mmol) according to the experimental provided in Tetrahedron 2002, 58, 5513. The product is recrystallized from EtOAc/Hexane. The yield is 136 mg of benzenesulfonohydrazide, 28%.

Workup

  1. customexperimental provided in Tetrahedron 2002, 58, 5513
  2. customThe product is recrystallized from EtOAc/Hexane

Sources & evidence

ORD record
ord-aa0c24f882f845a5b42ee00e2015d391
Source dataset
uspto-grants-2006_04
Patent number
US07026339B2

Reaction notes

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