Methanol → HCID 178484335, compound

HRID 1798807Notes

Reaction equation

HRID 1798807 reaction equation
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH2:8])=[O:7])=[CH:4][CH:3]=1.CO.CO[CH:15](OC)[N:16]([CH3:18])[CH3:17]>>[CH3:15][N:16](/[CH:18]=[N:8]/[C:6](=[O:7])[C:5]1[CH:9]=[CH:10][C:2]([OH:1])=[CH:3][CH:4]=1)[CH3:17]

Participants

4

Reactant 3

HCID 887MethanolHCID 650524-HydroxybenzamideHCID 78373Dimethylformamide dimethyl acetal

Product 1

HCID 178484335HCID 178484335, compound

Procedure

A solution of 4-hydroxybenzamide (5.58 g, 40 mmol) in 15 mL of dimethylformamide dimethyl acetal was stirred at 120° C. for 1.5 h with distillation of the product methanol. After cooling, the solid was collected and tritrarated with diethyl ether, DCM to give desired product.

Workup

  1. temperatureAfter cooling
  2. customthe solid was collected

Sources & evidence

ORD record
ord-66f5a7d0384b452ab560830aece1c90d
Source dataset
uspto-grants-2013_01
Patent number
US08343990B2

Reaction notes

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