Water → 3,6-difluoro-N-((tetrahydro-2H-pyran-4-yl)methyl)pyridin-2-amine
Reaction equation
[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[CH3:25][N:26]1[CH2:27][CH2:28][CH2:29][C:30]1=[O:31].[CH3:32][CH2:33][O:34][C:35]([CH3:36])=[O:37].[F:1][c:2]1[n:3][c:4]([F:9])[cH:5][cH:6][c:7]1[F:8].[O:10]1[CH2:11][CH2:12][CH:13]([CH2:16][NH2:17])[CH2:14][CH2:15]1.[OH2:38]>>[c:2]1([NH:17][CH2:16][CH:13]2[CH2:12][CH2:11][O:10][CH2:15][CH2:14]2)[n:3][c:4]([F:9])[cH:5][cH:6][c:7]1[F:8]Participants
7
Sources & evidence
- ORD record
- ord-c108c2da157b492c93fcf3e333859769
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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