Dichloromethane → 7,8-Dimethoxy-10-{[2-methyl-2'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl]carbonyl}-[(10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl)carbonyl]-4-piperidinone
Reaction equation
[CH3:1][O:2][c:3]1[c:4]([O:36][CH3:37])[cH:5][c:6]2[c:7]([cH:35]1)[CH2:8][n:9]1[c:10]([cH:32][cH:33][cH:34]1)[CH2:11][N:12]2[C:13](=[O:14])[c:15]1[cH:16][c:17]([CH3:31])[c:18](-[c:21]2[c:22]([C:27]([F:28])([F:29])[F:30])[cH:23][cH:24][cH:25][cH:26]2)[cH:19][cH:20]1.[CH3:46][CH2:47][N:48]([CH2:49][CH3:50])[CH2:51][CH3:52].[Cl:60][CH2:61][Cl:62].[NH:53]1[CH2:54][CH2:55][C:56](=[O:59])[CH2:57][CH2:58]1.[O:38]=[C:39]([Cl:40])[O:41][C:42]([Cl:43])([Cl:44])[Cl:45]>>[CH3:1][O:2][c:3]1[c:4]([O:36][CH3:37])[cH:5][c:6]2[c:7]([cH:35]1)[CH2:8][n:9]1[c:10]([cH:32][cH:33][c:34]1[C:39](=[O:38])[N:53]1[CH2:54][CH2:55][C:56](=[O:59])[CH2:57][CH2:58]1)[CH2:11][N:12]2[C:13](=[O:14])[c:15]1[cH:16][c:17]([CH3:31])[c:18](-[c:21]2[c:22]([C:27]([F:28])([F:29])[F:30])[cH:23][cH:24][cH:25][cH:26]2)[cH:19][cH:20]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c45588ea61ad4df681613fd80fed3a44
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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