Hydroxylamine → HCID 86615834, compound

HRID 1816857Notes

Reaction equation

HRID 1816857 reaction equation
[OH:1][NH2:2].[C:3]1(=[O:10])[O:9][C:7](=[O:8])[CH2:6][CH2:5][CH2:4]1>C1C=CC=CC=1.C(N(CC)CC)C>[C:3]([OH:9])(=[O:10])[CH2:4][CH2:5][CH2:6][C:7]([OH:1])=[O:8].[NH2:2][OH:1]

Participants

5

Reactant 2

HCID 787HydroxylamineHCID 7940Glutaric anhydride

Product 1

HCID 86615834HCID 86615834, compound

Reagents, catalysts & solvents 2

HCID 241BenzeneSolventHCID 8471TriethylamineSolvent

Procedure

This example that demonstrates how this method could be performed. Part 1: To a solution of 2 g hydroxy amine in 100 ml dry benzene and 20 ml triethyl amine, 9.4 g glutaric anhydride is added and the reaction mixture stirred at room temperature for 2 h and refluxed for 2 h. The solvent is evaporated under vacuum and the residue is purified by flash chromatography using silica gel.

Workup

  1. temperaturerefluxed for 2 h
  2. customThe solvent is evaporated under vacuum
  3. customthe residue is purified by flash chromatography

Sources & evidence

ORD record
ord-a216ed775ca2463b9eec0d964191bde0
Source dataset
uspto-grants-2009_10
Patent number
US07597882B2

Reaction notes

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