Triethylamine → HCID 24899700, compound

HRID 1819862Notes

Reaction equation

HRID 1819862 reaction equation
[CH2:1]1[C:9]2[C:8]3[CH:10]=[CH:11][CH:12]=[CH:13][C:7]=3[O:6][C:5]=2[CH2:4][CH2:3][CH:2]1[NH2:14].[N+:15]([C:18]1[CH:26]=[CH:25][C:21]([C:22](Cl)=[O:23])=[CH:20][CH:19]=1)([O-:17])=[O:16].C(N(CC)CC)C>O1CCCC1>[N+:15]([C:18]1[CH:19]=[CH:20][C:21]([C:22]([NH:14][C:2]2[CH:3]=[CH:4][C:5]3[O:6][C:7]4[CH2:13][CH2:12][CH2:11][CH2:10][C:8]=4[C:9]=3[CH:1]=2)=[O:23])=[CH:25][CH:26]=1)([O-:17])=[O:16]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 85024-Nitrobenzoyl chlorideHCID 21221605HCID 21221605, compound

Product 1

HCID 24899700HCID 24899700, compoundYield 81.3%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following the procedure of Example 1, tetrahydro-dibenzofuran-2-ylamine (2.8 g, 15 mmol), 4-nitrobenzoyl chloride (3.0 g, 16 mmol), and triethylamine (6.4 mL, 45 mmol) in tetrahydrofuran (60 mL) provided 4-nitro-N-(6,7,8,9-tetrahydro-dibenzofuran-2-yl)-benzamide (4.1 g). Mp 279-280° C.;Anal. Calcd. for C19H16N2O4: C, 67.85; H, 4.79; N, 8.33; Found: C, 67.69; H, 4.61; N, 8.26.

Sources & evidence

ORD record
ord-7ff59fd17fc54582ae230c4bf46c98ff
Source dataset
uspto-grants-2009_10
Patent number
US07601856B2

Reaction notes

Loading…