4-Chlorophenol → HCID 20561961, compound

HRID 1821714Notes

Reaction equation

HRID 1821714 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.[O:9]=[P:10](Cl)([Cl:12])[Cl:11].P(Cl)([Cl:17])([O-])=O>CCOCC>[P:10]([Cl:12])([Cl:11])([O:8][C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[C:3]([Cl:17])[CH:4]=1)=[O:9]

Participants

5

Reactant 3

HCID 46844-ChlorophenolHCID 24813Phosphorus oxychlorideHCID 3718378dichlorophosphate

Product 1

HCID 20561961HCID 20561961, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

3,4-Dichloro-phenyl dichlorophosphate was prepared as described in Example 2 from p-chlorophenol (3.79 g, 0.023 mol), POCl3 (2.17 mL, 0.023 mol) and TEA (3.25 mL, 0.023 mol) and dry Et2O (25 mL).The dichlorophosphate 11c was obtained as a yellow clear oil (2.93 g, 0.0105 mol, 45%) and used without further purification.

Sources & evidence

ORD record
ord-18604279dd4c4550bd0628e0857e566a
Source dataset
uspto-grants-2009_10
Patent number
US07608599B2

Reaction notes

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