Cinnamaldehyde → HCID 178477500, compound

HRID 1822589Notes

Reaction equation

HRID 1822589 reaction equation
O=C/C=C/c1ccccc1.CCSC(=O)C(C)C(=O)O>C1CCNCC1.CN(C)c1ccncc1.CN(C)C=O>CCSC(=O)/C(C)=C/C=C/c1ccccc1

Participants

6

Reactant 2

HCID 637511CinnamaldehydeHCID 15250913HCID 15250913, compound

Product 1

HCID 178477500HCID 178477500, compoundYield 72%

Reagents, catalysts & solvents 3

HCID 142844-(Dimethylamino)pyridineReagentHCID 8082PiperidineCatalystHCID 6228DimethylformamideSolvent

Conditions

Temperature
25 °C

Workup

  1. temperatureThe product mixture was cooled to 25 °C.
  2. filtrationFiltered through a pad of celite · Keep Organic
  3. wash"The celite was washed with ethyl acetate (3 x 1 mL)."
  4. concentrationThe filtrate was concentrated under reduced pressure
  5. additionA 0.07 M stock solution of the internal standard ethylene carbonate (0.70 mL in CDCl3) was added.

Sources & evidence

ORD record
ord-7aea1f59f5464366a62722fa1a1f13ad
Source dataset
Bayesian optimization of 5 decarboxylative olefination reactions

Reaction notes

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