Hydrochloric Acid → 286836-32-6

HRID 1824944Notes

Reaction equation

HRID 1824944 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH2:10][CH:11](N)[CH3:12])=[CH:9][C:4]=2[CH:3]=[CH:2]1.Cl.C(OCC)(=[O:17])C>C(OCC)C>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH2:10][C:11](=[O:17])[CH3:12])=[CH:9][C:4]=2[CH:3]=[CH:2]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 98372325-(2-Aminopropyl)benzofuran

Product 1

HCID 22144718286836-32-6Yield 91%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

This amine was dissolved in 20 mL ethyl acetate and then a 1 N solution of hydrogen chloride in diethyl ether was added dropwise. The resulting slurry was filtered, the solid washed with 3 mL ethyl acetate, and the solid dried under vacuum to provide 0.548 gm (91%) of the title compound.

Workup

  1. filtrationThe resulting slurry was filtered
  2. washthe solid washed with 3 mL ethyl acetate
  3. customthe solid dried under vacuum

Sources & evidence

ORD record
ord-33537da81d28443381d818022afc5fe4
Source dataset
uspto-grants-2006_05
Patent number
US07045545B1

Reaction notes

Loading…