反应详情

9.28 g (30 mmol) of N-[4-(2-amino-3,5-dicyano-6-sulphanyl-4-pyridinyl)phenyl]-acetamide, 7.38 g (45 mmol) of 2-picolyl chloride hydrochloride and 10.08 g (120 mmol) of sodium hydrogen carbonate are stirred at room temperature in 100 ml of DMF. After 2 hours, 100 ml of water are added dropwise at from 40 to 50° C.