Dimethylformamide dimethyl acetal → HCID 54080401, compound

HRID 1833286Notes

Reaction equation

HRID 1833286 reaction equation
[C:1]([P:4](=[O:11])([O:8][CH2:9][CH3:10])[O:5][CH2:6][CH3:7])(=[O:3])[NH2:2].CO[CH:14](OC)[N:15]([CH3:17])[CH3:16]>O1CCCC1>[CH3:14][N:15]([CH3:17])[CH:16]=[N:2][C:1]([P:4](=[O:11])([O:8][CH2:9][CH3:10])[O:5][CH2:6][CH3:7])=[O:3]

Participants

4

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 3692772HCID 3692772, compound

Product 1

HCID 54080401HCID 54080401, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

a solution of 54 parts of diethyl carbamoylphosphonate and 36 parts of dimethyl formamide dimethyl acetal was refluxed in 1000 parts of anhydrous tetrahydrofuran for eight hours. The solvent was removed under reduced pressure to give 70 parts of diethyl 1-dimethylaminomethyleneaminocarbonylphosphonate, nD24 = 1.4970.

Workup

  1. customThe solvent was removed under reduced pressure

Sources & evidence

ORD record
ord-604c31e06614499ba55501a3884b2024
Source dataset
uspto-grants-1978_01
Patent number
US04066434

Reaction notes

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