Ammonium → 9-Fluoro-5-(2-hydroxyethyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]diazepine-1-carboxylic acid 2-methyl-4-(2,3,4,5-tetrahydrobenzo[b]azepine-1-carbonyl)benzylamide
Reaction equation
[BH4-:49].[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[CH3:42][N:43]1[CH2:44][CH2:45][O:46][CH2:47][CH2:48]1.[Cl-:51].[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:12]1[N:11]([C:13]([NH:14][CH2:15][c:16]1[c:17]([CH3:35])[cH:18][c:19]([C:22](=[O:23])[N:24]3[c:25]4[c:26]([cH:31][cH:32][cH:33][cH:34]4)[CH2:27][CH2:28][CH2:29][CH2:30]3)[cH:20][cH:21]1)=[O:36])[CH2:10][CH2:9][C:8](=[O:37])[N:7]2[CH2:38][C:39](=[O:40])[OH:41].[NH4+:52].[Na+:50].[OH2:58]>>[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:12]1[N:11]([C:13]([NH:14][CH2:15][c:16]1[c:17]([CH3:35])[cH:18][c:19]([C:22](=[O:23])[N:24]3[c:25]4[c:26]([cH:31][cH:32][cH:33][cH:34]4)[CH2:27][CH2:28][CH2:29][CH2:30]3)[cH:20][cH:21]1)=[O:36])[CH2:10][CH2:9][C:8](=[O:37])[N:7]2[CH2:38][CH2:39][OH:40]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-061c607649874aa0b2bbd618657c3ed0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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