HCID 22677060, compound → HCID 22677059, compound

HRID 1837430Notes

Reaction equation

HRID 1837430 reaction equation
[CH3:1][Si:2]([CH3:16])([C:10]#[C:11][Si:12]([CH3:15])([CH3:14])[CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][OH:9]>C(O)C.C(OCC)(=O)C.[OH-].[OH-].[Pd+2]>[CH3:16][Si:2]([CH3:1])([CH2:10][CH2:11][Si:12]([CH3:13])([CH3:14])[CH3:15])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][OH:9]

Participants

5

Reactant 1

HCID 22677060HCID 22677060, compound

Product 1

HCID 22677059HCID 22677059, compound

Reagents, catalysts & solvents 3

HCID 9942167Palladium hydroxideCatalystHCID 702EthanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

A suspension of compound 16 (18.18 g, 0.071 mol) and palladium hydroxide on charcoal (2.46 g, 2.13 mmol) in ethanol and ethyl acetate (120 ml, 1:1) was stirred under an atmosphere of hydrogen for 24 h at room temperature. The reaction mixture was filtered (celite) and the solvent roved in vacuo to yield a clear oil.

Workup

  1. filtrationThe reaction mixture was filtered (celite)
  2. customto yield a clear oil

Sources & evidence

ORD record
ord-e2c3c2bb9e0b449ab5e8b4a1bcd90d4a
Source dataset
uspto-grants-2004_08
Patent number
US06783812B2

Reaction notes

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