Hydrochloric Acid → 1-[5-[[4-(1-Hydroxy-1-methylethyl)benzoyl]amino]-2-methylpyrazolo[1,5-a]pyrimidin-7-yl]-4-piperidineacetamide

HRID 184376Notes

Reaction equation

HRID 184376 reaction equation
[CH3:50][S:51]([CH3:52])=[O:53].[CH3:54][OH:55].[CH:36]([N:37]([CH2:38][CH3:39])[CH:40]([CH3:41])[CH3:42])([CH3:43])[CH3:44].[Cl:1][c:2]1[cH:3][c:4]([NH:12][C:13]([c:14]2[cH:15][cH:16][c:17]([C:20]([CH3:21])([CH3:22])[OH:23])[cH:18][cH:19]2)=[O:24])[n:5][c:6]2[n:7]1[n:8][c:9]([CH3:11])[cH:10]2.[ClH:25].[NH:26]1[CH2:27][CH2:28][CH:29]([CH2:32][C:33](=[O:34])[NH2:35])[CH2:30][CH2:31]1.[O:45]=[CH:46][N:47]([CH3:48])[CH3:49]>>[c:2]1([N:26]2[CH2:27][CH2:28][CH:29]([CH2:32][C:33](=[O:34])[NH2:35])[CH2:30][CH2:31]2)[cH:3][c:4]([NH:12][C:13]([c:14]2[cH:15][cH:16][c:17]([C:20]([CH3:21])([CH3:22])[OH:23])[cH:18][cH:19]2)=[O:24])[n:5][c:6]2[n:7]1[n:8][c:9]([CH3:11])[cH:10]2

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 679Dimethyl SulfoxideHCID 887MethanolHCID 6228DimethylformamideHCID 81531DiisopropylethylamineHCID 220649342-(Piperidin-4-yl)acetamideHCID 86652267N-(7-chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)-4-(2-hydroxypropan-2-yl)benzamide

Product 1

HCID 670647371-[5-[[4-(1-Hydroxy-1-methylethyl)benzoyl]amino]-2-methylpyrazolo[1,5-a]pyrimidin-7-yl]-4-piperidineacetamide

Sources & evidence

ORD record
ord-29654c7c119f46288a87dafaa596f8ee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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