Water → HCID 86663917, compound

HRID 1846473Notes

Reaction equation

HRID 1846473 reaction equation
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[N:5]=[CH:4][N:3]=1.[OH:9][C:10]1[CH:19]=[CH:18][C:13]2[NH:14][C:15](=[O:17])[O:16][C:12]=2[CH:11]=1.C(=O)([O-])[O-].[K+].[K+].O>CN(C=O)C>[Cl:8][C:6]1[N:5]=[CH:4][N:3]=[C:2]([O:9][C:10]2[CH:19]=[CH:18][C:13]3[NH:14][C:15](=[O:17])[O:16][C:12]=3[CH:11]=2)[CH:7]=1

Participants

6

Reactant 4

HCID 962WaterHCID 11430Potassium CarbonateHCID 709434,6-DichloropyrimidineHCID 1571672(3H)-Benzoxazolone, 6-hydroxy-

Product 1

HCID 86663917HCID 86663917, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

0.20 g (1.34 mmol) 4,6-dichloropyrimidine, 0.21 g (1.39 mmol) 6-hydroxy-2-benzoxazolinone and 0.20. g (1.45 mmol) potassium carbonate in 2.0 mL DMF were stirred for 2 h at RT. The reaction mixture was mixed with water. The precipitate formed was suction filtered, washed and dried.

Workup

  1. customThe precipitate formed
  2. filtrationfiltered
  3. washwashed
  4. customdried

Sources & evidence

ORD record
ord-6ac19a75da584696bc99a4bde18762b6
Source dataset
uspto-grants-2015_02
Patent number
US08952014B2

Reaction notes

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