Water → HCID 61277540, compound

HRID 1846474Notes

Reaction equation

HRID 1846474 reaction equation
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[N:5]=[CH:4][N:3]=1.[CH3:9][C:10]1[CH:11]=[C:12]([OH:19])[CH:13]=[CH:14][C:15]=1[N+:16]([O-:18])=[O:17].C(=O)([O-])[O-].[K+].[K+].O>CN(C=O)C>[Cl:8][C:6]1[CH:7]=[C:2]([O:19][C:12]2[CH:13]=[CH:14][C:15]([N+:16]([O-:18])=[O:17])=[C:10]([CH3:9])[CH:11]=2)[N:3]=[CH:4][N:5]=1

Participants

6

Reactant 4

HCID 962WaterHCID 11430Potassium CarbonateHCID 174123-Methyl-4-nitrophenolHCID 709434,6-Dichloropyrimidine

Product 1

HCID 61277540HCID 61277540, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

0.40 g (2.68 mmol) 4,6-dichloropyrimidine, 0.42 g (2.74 mmol) 3-methyl-4-nitrophenol and 0.40 g (2.89 mmol) potassium carbonate in 2.0 mL DMF were stirred for 2 h at RT. The reaction mixture was mixed with water and the precipitate formed was suction filtered, washed and dried.

Workup

  1. customthe precipitate formed
  2. filtrationfiltered
  3. washwashed
  4. customdried

Sources & evidence

ORD record
ord-5da7be80f6014fa49b3ec8a378df3a3f
Source dataset
uspto-grants-2015_02
Patent number
US08952014B2

Reaction notes

Loading…