反应详情

温度

50 °C

74 mg (0.42 mmol) 2-methoxy-4-methyl-1H-benzo[d]imidazol-6-ol and 68 mg (0.44 mmol) 4,6-dichloropyrimidine were placed in 2.0 mL DMF. 0.12 g (0.88 mmol) potassium carbonate were added and the mixture was stirred for 4 h at 50° C. The reaction mixture was combined with ice water, the substance was extracted with ethyl acetate and evaporated down i.vac.

1. extractionthe substance was extracted with ethyl acetate
2. customevaporated down i.vac