1,1-Dimethylhydrazine → HCID 20770452, compound

HRID 1855622Notes

Reaction equation

HRID 1855622 reaction equation
[CH3:1][N:2]([CH3:10])[NH:3][C:4](=[O:9])[C:5](C)([CH3:7])[CH3:6].CN(C)N.C(N(CC)CC)C.C(Cl)(=O)C(C)C>C(OCC)C>[CH3:1][N:2]([CH3:10])[NH:3][C:4](=[O:9])[CH:5]([CH3:7])[CH3:6]

Participants

6

Reactant 4

HCID 59761,1-DimethylhydrazineHCID 8471TriethylamineHCID 62325Isobutyryl chlorideHCID 20156813HCID 20156813, compound

Product 1

HCID 20770452HCID 20770452, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

In a fashion similar to the preparation of LtBu,NMe2H, treatment of a diethyl ether (250 mL) solution of 1,1-dimethylhydrazine (3.88 mL, 50 mmol) and triethylamine (7.52 mL, 53 mmol) with isobutyryl chloride (5.39 mL, 50 mmol) afforded LiPr,NMe2H as colorless crystals upon crystallization from Et2O and subsequent sublimation at 60° C./0.05 Torr (6.12 g, 94%): mp 94-96° C.

Sources & evidence

ORD record
ord-305c765fd8054ed5aa21f60b66147a7b
Source dataset
uspto-grants-2015_02
Patent number
US08962876B2

Reaction notes

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