Hydrochloric Acid → HCID 23347222, compound

HRID 1855965Notes

Reaction equation

HRID 1855965 reaction equation
[C:1]1([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:6]=[CH:5][C:4]([C:7]([CH2:20][CH2:21][N:22]([CH:26]([CH3:28])[CH3:27])[CH:23]([CH3:25])[CH3:24])([CH2:11][CH2:12][N:13]([CH:17]([CH3:19])[CH3:18])[CH:14]([CH3:16])[CH3:15])[C:8]([NH2:10])=[O:9])=[CH:3][CH:2]=1.CCOCC.[ClH:40]>C(O)(C)C>[ClH:40].[ClH:40].[C:1]1([C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)[CH:6]=[CH:5][C:4]([C:7]([CH2:11][CH2:12][N:13]([CH:14]([CH3:16])[CH3:15])[CH:17]([CH3:18])[CH3:19])([CH2:20][CH2:21][N:22]([CH:23]([CH3:24])[CH3:25])[CH:26]([CH3:28])[CH3:27])[C:8]([NH2:10])=[O:9])=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 23347223HCID 23347223, compound

Product 1

HCID 23347222HCID 23347222, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

To a solution of 10 parts of α-(4-biphenylyl)-α,α-bis[2-(diisopropylamino)ethyl]acetamide in 350 parts by volume of ether is added dropwise with stirring 2 molar equivalents of hydrochloric acid in isopropyl alcohol. The mixture is stirred for about 2 hours when the resulting salt is separated by filtration to afford α-(4-biphenylyl)-α,α-bis[2-(diisopropylamino)ethyl]acetamide dihydrochloride, as a solid.

Workup

  1. customis separated by filtration

Sources & evidence

ORD record
ord-1bbed574623f4bf1b292c9ce1317cd85
Source dataset
uspto-grants-1980_08
Patent number
US04217306

Reaction notes

Loading…