Ethyl Acetate → HCID 53634814, compound

HRID 1856222Notes

Reaction equation

HRID 1856222 reaction equation
[F:1][C:2]([F:19])([F:18])[C:3]1[C:11]([C:12]([F:15])([F:14])[F:13])=CC=C2[C:4]=1[C:5](=O)[C:6](=O)[NH:7]2.ClC1C=CC=C(C(OO)=[O:28])C=1.[C:31]([O:34][CH2:35][CH3:36])(=[O:33])C>>[F:1][C:2]([F:18])([F:19])[C:3]1[C:11]([C:12]([F:13])([F:14])[F:15])=[C:36]2[C:35]([O:34][C:31](=[O:33])[NH:7][C:6]2=[CH:5][CH:4]=1)=[O:28]

Participants

4

Reactant 3

HCID 8857Ethyl AcetateHCID 70297m-Chloroperbenzoic acidHCID 23346412HCID 23346412, compound

Product 1

HCID 53634814HCID 53634814, compound

Procedure

4,5-Bis(trifluoromethyl)isatin (283 g., 1 mol.) is suspended in 1 L. of ethyl acetate and treated with m-chloroperbenzoic acid (172 g., 1 mol.), stirred until the oxidation is complete to yield 5,6-bis(trifluoromethyl)-isatoic anhydride.

Sources & evidence

ORD record
ord-1339e42314c049619a7aff84a371a113
Source dataset
uspto-grants-1980_08
Patent number
US04218464

Reaction notes

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