Hydrochloric Acid → HCID 15484977, compound

HRID 1857583Notes

Reaction equation

HRID 1857583 reaction equation
[CH:1]1([S:6]([NH2:9])(=[O:8])=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.[OH-].[Na+].[Br:12][C:13]1[CH:18]=[CH:17][C:16]([N:19]=[C:20]=[O:21])=[CH:15][CH:14]=1.Cl>CC(C)=O>[Br:12][C:13]1[CH:18]=[CH:17][C:16]([NH:19][C:20]([NH:9][S:6]([CH:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)(=[O:8])=[O:7])=[O:21])=[CH:15][CH:14]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 756094-Bromophenyl isocyanateHCID 4645983Cyclopentanesulfonamide

Product 1

HCID 15484977HCID 15484977, compoundYield 83.2%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

The general method of procedure A was followed with cyclopentanesulfonamide (3 g), acetone (100 ml), 1N sodium hydroxide (21 ml), and 4-bromophenyl isocyanate (3.7 g) dissolved in acetone (50 ml). After two hours, 1N HCl (21 ml) was added. The resulting precipitate was collected, washed with water and dried at 60° C. under vacuum to provide 5.4 g of product.

Workup

  1. customThe resulting precipitate was collected
  2. washwashed with water
  3. customdried at 60° C. under vacuum

Sources & evidence

ORD record
ord-2a2a84b0c2194bf196738fcc6bb7b1e7
Source dataset
uspto-grants-2000_11
Patent number
US06147115

Reaction notes

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