Ethyl Glycolate → Ethyl [(phenoxycarbonyl)oxy]acetate

HRID 1867541Notes

Reaction equation

HRID 1867541 reaction equation
[C:1]([O:5][CH2:6][CH3:7])(=[O:4])[CH2:2][OH:3].C(N(C(C)C)CC)(C)C.Cl[C:18]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:19]>C1(C)C=CC=CC=1>[C:21]1([O:20][C:18]([O:3][CH2:2][C:1]([O:5][CH2:6][CH3:7])=[O:4])=[O:19])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

5

Reactant 3

HCID 12184Ethyl GlycolateHCID 15891Phenyl chloroformateHCID 81531Diisopropylethylamine

Product 1

HCID 12094709Ethyl [(phenoxycarbonyl)oxy]acetate

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A solution of 25 g (240 mmol) of ethyl glycolate and 55 ml (315 mmol) of diisopropylethylamine in 500 ml of toluene is admixed slowly at ambient temperature with 32 ml (256 mmol) of phenyl chloroformate. Stirring is continued at ambient temperature for 2 hours.

Sources & evidence

ORD record
ord-c00dad19c4654875ac7fb37e6ac54edb
Source dataset
uspto-grants-2009_12
Patent number
US07632850B2

Reaction notes

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