1,2-Dichloroethane → 3-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-N-[2-oxo-3-(3,4,5-trifluorophenyl)piperidin-1-yl]prop-2-enamide
Reaction equation
[CH2:1]([Cl:2])[CH2:3][Cl:4].[CH3:15][O:16][c:17]1[c:18](-[n:28]2[cH:29][n:30][c:31]([CH3:33])[cH:32]2)[cH:19][cH:20][c:21]([CH:23]=[CH:24][C:25](=[O:26])[OH:27])[n:22]1.[CH3:56][CH2:57][O:58][C:59](=[O:60])[CH3:61].[NH2:34][N:35]1[C:36](=[O:50])[CH:37]([c:41]2[cH:42][c:43]([F:49])[c:44]([F:48])[c:45]([F:47])[cH:46]2)[CH2:38][CH2:39][CH2:40]1.[O:51]=[CH:52][N:53]([CH3:54])[CH3:55].[OH2:62].[OH:5][n:6]1[c:7]2[c:8]([cH:9][cH:10][cH:11][cH:12]2)[n:13][n:14]1>>[CH3:15][O:16][c:17]1[c:18](-[n:28]2[cH:29][n:30][c:31]([CH3:33])[cH:32]2)[cH:19][cH:20][c:21]([CH:23]=[CH:24][C:25](=[O:27])[NH:34][N:35]2[C:36](=[O:50])[CH:37]([c:41]3[cH:42][c:43]([F:49])[c:44]([F:48])[c:45]([F:47])[cH:46]3)[CH2:38][CH2:39][CH2:40]2)[n:22]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e1d1ec53e2694526873e8833f19a4795
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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