反应详情

In the same manner as in Reference Example 5 and using 1,3-dimethyl-N-{2-methyl-5-[(6-{[(4-methylphenyl)sulfonyl]amino}pyridin-3-yl)oxy]phenyl}-1H-pyrazole-5-carboxamide (2.91 g, 5.92 mmol), N,N-diisopropylethylamine (1.34 mL, 7.70 mmol), iodoacetamide (1.42 g, 7.70 mmol) and N,N-dimethylformamide (15 mL) as starting materials, the title compound (2.35 g, 72%) was obtained as a white solid.