Piperazine → 2-(Piperazin-1-yl)-4-(trifluoromethyl)pyrimidine
Reaction equation
[CH2:12]1[CH2:13][NH:14][CH2:15][CH2:16][NH:17]1.[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[n:7]1.[O:25]=[CH:26][N:27]([CH3:28])[CH3:29]>>[c:2]1([N:14]2[CH2:13][CH2:12][NH:17][CH2:16][CH2:15]2)[n:3][cH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[n:7]1Participants
5
Sources & evidence
- ORD record
- ord-2fecb2613a644b579aae0087d8e01662
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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