Potassium Carbonate → HCID 19880164, compound

HRID 1885254Notes

Reaction equation

HRID 1885254 reaction equation
[Cl:1][C:2]1[C:10]([OH:11])=[C:9]([OH:12])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[C:13](=[O:16])([O-])[O-].[K+].[K+].[CH3:19][O:20][C:21]1[CH:28]=[CH:27][C:24]([CH2:25]Br)=[CH:23][CH:22]=1>CN(C)C=O>[Cl:1][C:2]1[C:10]([O:11][CH2:25][C:24]2[CH:27]=[CH:28][C:21]([O:20][CH3:19])=[CH:22][CH:23]=2)=[C:9]([O:12][CH2:4][C:3]2[CH:7]=[CH:8][C:9]([O:16][CH3:13])=[CH:10][CH:2]=2)[CH:8]=[CH:7][C:3]=1[C:4]([O:6][CH2:25][C:24]1[CH:27]=[CH:28][C:21]([O:20][CH3:19])=[CH:22][CH:23]=1)=[O:5]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 1650214-Methoxybenzyl bromideHCID 156081642-Chloro-3,4-dihydroxybenzoic acid

Product 1

HCID 19880164HCID 19880164, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

2-Chloro-3,4-dihydroxybenzoic acid is p-methoxybenzylated with potassium carbonate and p-methoxybenzyl bromide in dimethylformamide to give p-methoxybenzyl 2-chloro-3,4-bis(p-methoxybenzyloxy)benzoate. This is hydrolyzed with sodium hydroxide to give 2-chloro-3,4-bis(p-methoxybenzyloxy)benzoic acid.

Sources & evidence

ORD record
ord-169b281015cf4e8e8014796626546f75
Source dataset
uspto-grants-1992_09
Patent number
US05143910

Reaction notes

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