Hydrogen Peroxide → HCID 15746742, compound

HRID 1886218Notes

Reaction equation

HRID 1886218 reaction equation
[C:1]([NH:4][C:5](=[O:11])[CH2:6][CH2:7][C:8]([OH:10])=[O:9])(=[O:3])[NH2:2].[OH:12]O.O>CS(O)(=O)=O>[C:1]([NH:4][C:5](=[O:11])[CH2:6][CH2:7][C:8]([O:10][OH:12])=[O:9])(=[O:3])[NH2:2]

Participants

5

Reactant 3

HCID 784Hydrogen PeroxideHCID 962WaterHCID 12398891HCID 12398891, compound

Product 1

HCID 15746742HCID 15746742, compound

Reagents, catalysts & solvents 1

HCID 6395Methanesulfonic AcidSolvent

Conditions

Temperature
15 °C

Procedure

80 g (0.5 mol) of N-carbamoylsuccinamic acid are dissolved in 160 g of methanesulfonic acid and the solution is cooled to 15° C. 60 g (1.5 mol) of hydrogen peroxide (85% strength by weight) are added dropwise with cooling at such a rate that the internal temperature can be maintained between 15° and 20° C. The reaction mixture is stirred at 20° C. for 10 minutes, then cooled to 10° C. and admixed with water added dropwise with cooling. The precipitated peroxycarboxylic acid is filtered off with suction, washed free of mineral acid with water and dried at 40° C. under an aspirator vacuum.

Workup

  1. temperaturewith cooling at such a rate that the internal temperature
  2. temperaturecan be maintained between 15° and 20° C
  3. temperaturecooled to 10° C.
  4. additionadded dropwise
  5. temperaturewith cooling
  6. filtrationThe precipitated peroxycarboxylic acid is filtered off with suction
  7. washwashed free of mineral acid with water
  8. customdried at 40° C. under an aspirator vacuum

Sources & evidence

ORD record
ord-aac4096e39be472fb1a9e669fc95f292
Source dataset
uspto-grants-1992_09
Patent number
US05149864

Reaction notes

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