反应详情

50% Aqueous citric acid solution is added to about 0.5 L of Banamine Solution while maintaining the temperature at less than 30° C. The resulting mixture was agitated for about 1 hour while continuing to maintain the temperature at less than 30° C. The precipitated Flunixin was collected by filtration and washed with 0.5 L of water, then dried at about 50-60° C. to a moisture content of less than 1% to yield about 23.5 g of crude Flunixin (94%)

1. temperaturewhile maintaining the temperature at less than 30° C
2. temperatureto maintain the temperature at less than 30° C
3. filtrationThe precipitated Flunixin was collected by filtration
4. washwashed with 0.5 L of water
5. customdried at about 50-60° C. to a moisture content of less than 1%